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tirzepatide and sugar intake Tirzepatide decreases activation of the brain to high-fat, high-sugar food photos in the medial frontal and cingulate gyri, orbitofrontal cortex and hippocampus. This brain effect may explain in part reduced food intake

Marsoni M251S
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SURPASSEARLY evaluated starting tirzepatide early in type 2 diabetes vs. conventional step therapy. In adults with early T2D on metformin, tirzepatide produced larger 2year reductions in HbA1c Scott Isaacs, MD, FACP, FACE Gala GLP 1 Zepbound Tirzepatide Dosage Guide Trizepatide Dosages and Units TikTok Telehealth recommendations in California for Tirzepatide? : r tirzepatidecompound What Is Zepbound (tirzepatide)? Uses, Side Effects, Dosage GoodRx
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Jimmy
West Palm Beach, US
★★★★★ 5
Great quality! Sadie loves her dental bone!
Love all playology toys. Good for their teeth - vet recommended - and my shepherd can’t destroy them. She loves all her new playology toys we got her for Christmas!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 26, 2025
E
Verified Purchase
edward j boisseau
Charlottesville, US
★★★★★ 1
Something “new” is not always an improvement
My dog has absolutely no interest in this. Looks like I fell victim to good marketing. Save your money and buy something your dog has enjoyed in the past. Something new is not always better.
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Reviewed in the United States on December 3, 2025
P
Verified Purchase
Puzzle Lover
Alexandria, US
★★★★★ 2
Disappointed
It arrived on time and as advertised. I actually ordered 2 of the Playology toys and my boy did not like either. Total waste of $40 for the 2 toys. The toys are did not smell(to me at least) like the scent they advertised and my boy is sooooo food motivated and such a chewer that I was sure he would love these. Hasn’t touched them since the day I gave them to him. Very disappointed.
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Reviewed in the United States on July 1, 2025
T
Verified Purchase
Teresa Rafeek
Massapequa, US
★★★★★ 2
Not Rottweiler proof
Lasted about an hour.
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Reviewed in the United States on November 13, 2025
K
Verified Purchase
Ksett
Waukegan, US
★★★★★ 5
Excellent dog chew
Size: Small (Pack of 1)
Our dog loves this and uses it everyday. Still going strong 3 months later.
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Reviewed in the United States on May 11, 2026

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