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dual glp-1/glucagon receptor agonists SCALE (NEJM 2015) was the pivotal trial for liraglutide 3.0 mg — the first GLP-1 RA approved for chronic weight management. In 3,731 adults with obesity, it produced 8.0% mean weight loss

Marsoni M251S
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Amazon Customer
Birmingham, US
★★★★★ 3
Not going to last long with a chewer
Color: Michigan Wolverines
Chewed up the first day!! Not built to last
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Reviewed in the United States on October 24, 2025
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Janice A. Byrne
Boise, US
★★★★★ 5
Great
Color: Ohio State Buckeyes
Luna.loved it
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Reviewed in the United States on September 30, 2024
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Timothy L Maret
Houston, US
★★★★★ 5
Looks sturdy and durable
Color: Ohio State Buckeyes
Purchased as a gift for a friends dog. She plays with it alot. It looked sturdy and felt durable.
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Reviewed in the United States on December 17, 2022
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MEL
Dallas, US
★★★★★ 4
Dog loves it!
Color: Texas Longhorns
Dog loves it, but came with a big faded line across the bone
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Reviewed in the United States on September 2, 2025
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Dennis Elkins
Boise, US
★★★★★ 2
Not for big chewers.
Color: Ohio State Buckeyes
Brutus made short with of this thing. Ripped it open and you're off the ring. The ring last a long time.
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Reviewed in the United States on February 28, 2026

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